ikbguИзвестия Кабардино-Балкарского государственного университетаProceedings of the Kabardino-Balkarian State University2221-7789Kabardino-Balkarian State University named after Kh. M. Berbekov10.31143/2221-7789-2023-1-34-40UYVSBKikbgu-221Research ArticleХимияChemistryМЕХАНИЧЕСКИЕ, АНТИБАКТЕРИАЛЬНЫЕ И АНТИПРОЛИФЕРАТИВНЫЕ СВОЙСТВА ИРИДИЙ- И РОДИЙСОДЕРЖАЩИХ ХИТОЗАНОВЫХ ПЛЁНОКMECHANICAL, ANTIBACTERIAL AND ANTIPROLIFERATING PROPERTIES OF IRIDIUM- AND RHODIUM-CONTAINING CHITOSAN FILMSГодзишевскаяА. А.GodzishevskayaA. A.kovalevskaya2804@mail.ruЛопашиноваЕ. П.LopashinovaE. P.kovalevskaya2804@mail.ruНиколаевА. А.NikolaevA. A.kovalevskaya2804@mail.ruКурасоваМ. Н.KurasovaM. N.kovalevskaya2804@mail.ruКритченковА. С.KritchenkovA. S.kovalevskaya2804@mail.ruАндрееваО. И.AndreevaO. I.kovalevskaya2804@mail.ruРоссийский университет дружбы народовPeoples' Friendship University of Russia2023310320231313440Copyright © Годзишевская А.А., Лопашинова Е.П., Николаев А.А., Курасова М.Н., Критченков А.С., Андреева О.И., 20232023Годзишевская А.А., Лопашинова Е.П., Николаев А.А., Курасова М.Н., Критченков А.С., Андреева О.И.Godzishevskaya A.A., Lopashinova E.P., Nikolaev A.A., Kurasova M.N., Kritchenkov A.S., Andreeva O.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.izvestiakbsu.ru/jour/article/view/221

Получены родий – и иридийсодержащие плёнки на основе природного полимера хитозана, пластифицированные глицерином. В этой работе проведён комплексный анализ полученных материалов методами рентгенофазового анализа (РФА), рентгеноспектрального анализа (РСА), сканирующей электронной микроскопии (СЭМ), также изучены механические характеристики и биологические свойства (антибактериальная и антипролиферативная активность) полученных плёнок. Анализ механических свойств плёнок показал, что иридийсодержащие образцы, характеризуются более высокими ме- ханическими свойствами, чем родийсодержащие образцы. Таким образом, можно сделать вывод о том, что природа металлоцентра влияет на механические свойства плёнок. Иридиевые плёнки обладают большей антибактериальной активностью, чем соответствующие родиевые плёнки. Антипро- лиферативная активность исследуемых образцов обусловлена содержанием родия (III) и иридия (IV) и практически не зависит от природы вводимых катионов металлов.

Rhodium – and iridium-containing films based on the natural polymer of chitosan plasticized with glycerol have been obtained. In this work, a comprehensive analysis of the materials obtained by X-ray phase analysis (XRD), X-ray spectral analysis (XRD), scanning electron microscopy (SEM) was carried out, and the mechanical characteristics and biological properties (antibacterial and antiproliferative activity) of the obtained films were also studied. An analysis of the mechanical properties of the films showed that iridium-containing samples are character- ized by higher mechanical properties than rhodium-containing samples. Thus, we can conclude that the nature of the metal center affects the mechanical properties of the films. Iridium films have greater antibacterial activity than the corresponding rhodium films. The antiproliferative activity of the studied samples is due to the content of rhodium

(III) and iridium (IV) and is practically independent of the nature of the introduced metal cations.

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The authors declare that there are no conflicts of interest present.