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MECHANICAL, ANTIBACTERIAL AND ANTIPROLIFERATING PROPERTIES OF IRIDIUM- AND RHODIUM-CONTAINING CHITOSAN FILMS

https://doi.org/10.31143/2221-7789-2023-1-34-40

EDN: UYVSBK

Abstract

Rhodium – and iridium-containing films based on the natural polymer of chitosan plasticized with glycerol have been obtained. In this work, a comprehensive analysis of the materials obtained by X-ray phase analysis (XRD), X-ray spectral analysis (XRD), scanning electron microscopy (SEM) was carried out, and the mechanical characteristics and biological properties (antibacterial and antiproliferative activity) of the obtained films were also studied. An analysis of the mechanical properties of the films showed that iridium-containing samples are character- ized by higher mechanical properties than rhodium-containing samples. Thus, we can conclude that the nature of the metal center affects the mechanical properties of the films. Iridium films have greater antibacterial activity than the corresponding rhodium films. The antiproliferative activity of the studied samples is due to the content of rhodium

(III) and iridium (IV) and is practically independent of the nature of the introduced metal cations.

About the Authors

A. A. Godzishevskaya
Peoples' Friendship University of Russia
Russian Federation


E. P. Lopashinova
Peoples' Friendship University of Russia
Russian Federation


A. A. Nikolaev
Peoples' Friendship University of Russia
Russian Federation


M. N. Kurasova
Peoples' Friendship University of Russia
Russian Federation


A. S. Kritchenkov
Peoples' Friendship University of Russia
Russian Federation


O. I. Andreeva
Peoples' Friendship University of Russia
Russian Federation


References

1. Kankala R.K., Liu C.G., Yang D.Y., Wang S.B., Chen A.Z. Ultrasmall platinum nanoparticles enable deep tumor penetration and synergistic therapeutic abilities through free radical species-assisted catalysis to combat cancer multidrug resistance // Chemical Engineering Journal. 2020. V. 383. P. 123–138.

2. Kesavan S., Meena K.S., Dhakshinamoorthy R. Bioactive polysaccharides based graphene oxide na- noparticle as a promising carrier for anticancer drug delivery // Biointerface Res. Appl. Chem. 2022. V. 12. P. 3429–3445.

3. Malinowska-Pańczyk E., Staroszczyk H., Gottfried K., Kołodziejska I., Wojtasz-Pająk A. Antimicro- bial properties of chitosan solutions, chitosan films and gelatin-chitosan films // Polimery. 2015. V. 60, N 11-12.

4. P. 735–741.

5. Yuan D., Hao X., Liu G., Yue Y., Duan J. A novel composite edible film fabricated by incorporating W/O/W emulsion into a chitosan film to improve the protection of fresh fish meat // Food Chemistry. 2022.

6. V. 385. P. 132–647.

7. Guan G., Zhang L., Zhu J., Wu H., Li W., Sun Q. Antibacterial properties and mechanism of biopol- ymer-based films functionalized by CuO/ZnO nanoparticles against Escherichia coli and Staphylococcus aureus // Journal of Hazardous Materials. 2021. V. 402. P. 123–542.

8. Han H., Xu X., Kan H., Tang Y., Liu C., Wen H., Wu L., Jiang Y., Wang Z., Liu J. Wang F. Syner- gistic photodynamic/photothermal bacterial inactivation over heterogeneous quaternized chitosan/silver/cobalt phosphide nanocomposites // Journal of Colloid and Interface Science. 2022. V. 616. P. 304–315.

9. El-Hefian E.A., Nasef M.M., Yahaya A.H. The preparation and characterization of chitosan/poly (vi- nyl alcohol) blended films // E-journal of chemistry. 2010. V. 7, N 4. P. 1212–1219.

10. Muxika A., Etxabide A., Uranga J., Guerrero P., De La Caba K. Chitosan as a bioactive polymer: Pro- cessing, properties and applications // International journal of biological macromolecules. 2017. V. 105.

11. P. 1358–1368.

12. Rahman A.-U., Choudhary M.I., Thomson J. Techniques for Drug Development. London: CRC Press, 2001. 217 p.

13. Dubrovskiy I.G. The effect of biologically active complex compounds of platinum on root branching of cucumber seedlings // Ph.D. diss. PhD, Moscow, 1986 (in Russian).

14. Ivanov V.B. Using the roots as test objects for the assessment of biological action of chemical sub- stances // Russian Journal of Plant Physiology. 2011. V. 58. P. 1082–1089.


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For citations:


Godzishevskaya A.A., Lopashinova E.P., Nikolaev A.A., Kurasova M.N., Kritchenkov A.S., Andreeva O.I. MECHANICAL, ANTIBACTERIAL AND ANTIPROLIFERATING PROPERTIES OF IRIDIUM- AND RHODIUM-CONTAINING CHITOSAN FILMS. Proceedings of the Kabardino-Balkarian State University. 2023;13(1):34-40. https://doi.org/10.31143/2221-7789-2023-1-34-40. EDN: UYVSBK

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ISSN 2221-7789 (Print)